spinal paraganglioma radiology

J Craniovertebr Junction Spine. A combination of CT scanning and contrast-enhanced MRI is the imaging regimen of choice. We present a case spinal paraganglioma of the cauda equina in a 75-year-old male with an emphasis on magnetic resonance imaging and conventional angiography findings. However, imaging studies may play a crucial role in the decision making of surgical intervention. Paraganglioma Although spinal paragangliomas are rare, they are the third most common primary tumor to arise in the filum terminale (after ependymoma and astrocytoma). Conclusions: 68 Ga-DOTATATE PET/CT showed a significantly superior detection rate of spinal bone metastases compared to 18 F-FDG PET/CT and MRI of the spine. No. This review is based on a presentation given by Adam Flanders and adapted for the Radiology Assistant by Robin Smithuis. the complete spine (23). The 14 patients were followed up for 14-68 months (mean 39.4 months). Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Spine, fourth edition, is an invaluable resource for general radiologists, neuroradiologists, and trainees—anyone who requires an easily accessible, highly visual reference on today’s spinal imaging. Figure 1a. Open Table of Contents: Glomus Vagale Paraganglioma. Thoracic Paragangliomas are neuroendocrine tumours that rarely occur in the central nervous system. References. Solymosi L, Ferbert A: A case of spinal paraganglioma. The treatment of paraganglioma has historically been controversial. combination of clinical, pathological and imaging correlation should be done for better diagnosis. Chen G (1), Luo Z, Liu T, Yang H. Author information: (1)Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China. Keywords: Paraganglioma, spinal neoplasms, intradural, extramedullary Introduction Intra-dual extra-medullary tumors comprises up to 70 to 80% of the spinal canal tumors [1]. The study was conducted through retrospective analysis of the files of the patients who had undergone surgery with pre-diagnosis of spinal intradural tumor between 2011 and 2017 and diagnosed with paraganglioma. MR imaging has been proven to be an excellent technique for evaluating spinal and paraspinal lesions because of its superior soft tissue contrast and the ease of imaging in virtually any anatomic plane (8, 10, 13, 24, 25). Our patient represents what we believe to be the first reported case of a primary intradural thoracic paraganglioma. Pheochromocytomas are catecholamine-secreting tumors of the adrenal medulla chromaffin cells. The term “paraganglioma” is a generic one applied to tumors arising from paraganglia regardless of location [1, 2]. Radiologists, technologists, administrators, and industry professionals can find information and conduct e-commerce in MRI, mammography, ultrasound, x-ray, CT, nuclear medicine, PACS, and other imaging disciplines. Financial support and sponsorship Nil. Paragangliomas arising within the spinal canal are rare and when they occur are usually found in the intradural, extramedullary compartment and in the lum … We report a case of a 41-year-old man with a primary thoracic spine paraganglioma presenting with spinal cord compression and distant metastasis. It was not until the 1960s that diagnostic imaging devices (ie, arteriography and tomography) became sophisticated enough to accommodate surgical anatomic needs. and in the lumbosacral region. Few reports of this functioning disorder appear in the literature. Their clinicopathologic data and imaging findings were retrospectively reviewed. primary epidural paragangliomas in the thoracic spine (1-7]. CLINICAL FEATURES. Treatment of Paraganglioma. Surgery revealed a paraganglioma. A combination of CT scanning and contrast-enhanced MRI is the imaging regimen of choice. Spinal paragangliomas are tumors of neuroendocrine origin that rarely involve the central nervous system, usually the filum terminale and cauda equina. They are indolent and considered WHO grade I lesions 5 . MR imaging studies of these lesions typically reveal a well-circumscribed mass that is isointense relative to the spinal cord on T1WI and iso- to hyperintense on T2WI 42. Spinal paragangliomas are uncommon, and among these, paragangliomas of the thoracic spine are distinctly unusual. Extraadrenal paragangliomas involving the spine is less common and usually takes the form of intradural compression of the cauda equina. Drs. CASE REPORT Computerized Radiol. We report a case of a patient with a history of an extra-adrenal non-functional paraganglioma of the jugular foramen which was initially treated with intra-arterial embolization. Functional Magnetic Resonance Imaging (fMRI) Functional laser Doppler functional Imaging (fLDI) Aging, traumatic brain injury, spinal cord injury and epilespy Brain energetics, mitochondrial function and neuroprotective interventions in vivo against traumatic brain injury and aging Image processing and multivariate statistical methods Summary: Spinal intradural extramedullary capillary hemangiomas are extremely rare. involves the cervical spine, where it may make surgical resection challenging. Functioning paraganglioma of the cervical spine. Magnetic resonance imaging is the optimum mode of imaging for visualization of spinal paraganglioma . Methods: The clinical and follow-up data of 18 patients who were diagnosed of spinal paraganglioma and treated with surgeries in our hospitals from 2003 to 2014 were retrospectively analyzed. IMAGING RECOMMENDATIONS. On MRI, paragangliomas are well circumscribed and hyperintense on T2-weighted imaging and avidly enhance on contrast-enhanced imaging (Figs. COVID-19 Safety Precautions: Find the Latest Visitor and Mask Policies. Introduction. Mishra T, Goel NA, Goel AH: Primary paraganglioma of the spine: A clinicopathological study of eight cases. Figure 1: (Top Left) T1WI demonstrates a low-signal-intensity mass in the typical location of the vagus nerve along the carotid space. 7A, 7B, 7C, and 7D). Imaging tests. Less commonly, malignant peripheral nerve sheath tu-mor commonly mimics the imaging appearance of a schwannoma but has decidedly more aggressive biologic behavior. Imaging tests create pictures of the paraganglioma to help your doctor better understand the extent of the tumor and help determine the best treatment options. For each tumour, site, size, MRI characteristics, CT appearances and enhancement after gadolinium and iohexol were recorded. The morphologic and immunohistochemical features strongly suggest a neuroendocrine neoplasm. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Learn More A 49-year-old man was admitted to hospital for treatment of a T10-11 paraspinal lesion, which was detected incidentally. Current imaging evaluation of patients with spinal canal paragangliomas is nonspecific and similar to the evaluation for other intraspinal mass lesions. Paragangliomas are rare neuroendocrine tumors that present in the spinal cord in only 10% of cases. MR Findings of the Spinal Paraganglioma: Report of Three Cases Joo Yong Shin, Sung Moon Lee, Mee Young Hwang, * Cheol Ho Sohn and Soo Jhi Suh Department of Diagnostic Radiology, Keimyung University School of Medicine, Korea. is a neuroradiologist, formerly at the National Institutes of Health and now at Doctors Community Hospital, Lanham, MD. BASIC DESCRIPTION. Extra-adrenal pheochromocytomas are called paragangliomas and only rarely produce catecholamine excess (13, 14). 167-170, 1986 0730-4862/86 $3.00 + 0.00 Printed in the U.S.A. Pergamon Journals Ltd PARAGANGLIOMA METASTATIC TO THE CERVICAL SPINE ROBIN E. OSBORN and SAEID MOJTAHEDI The University of Chicago Medical Center, Department of Radiology, 5841 South Maryland Avenue, Chicago, IL 60637, U.S.A. (Received 5 February 1986; in revised form 22 … From cases reviewed in the literature, on T1 weighted imaging the tumors were isointense to the spinal cord in 76.6% of patients. is usually considered as standard management. It was not until the 1960s that diagnostic imaging devices (ie, arteriography and tomography) became sophisticated enough to accommodate surgical anatomic needs. The three patients were men who had symptoms of either myelopathy (n = 2) or radiculopathy (n = 1). Tests may include MRI, CT, and specialized nuclear medicine imaging such as a metaiodobenzylguanidine (MIBG) scan and a positron emission tomography (PET) scan. We present a case report of a 56-year-old woman with acute foot drop with no previous significant background history. We present the case of a 46-year-old female with a lumbar spine paraganglioma. This is the first case of a functioning cervical spinal paraganglioma with symptoms of catecholamine excess throughout the operation. appearance associated with head-and-neck paragangliomas may be seen. Spinal metastases of carotid paraganglioma. Current imaging evaluation of patients with spinal canal paragangliomas is nonspecific and similar to the evaluation for other intraspinal mass lesions. Result: A total of fourteen patients radiographed of intra-spinal tumor underwent extra-capsular tumor resection. Both anatomical and functional imaging of paragangliomas is required for At this location paraganglioma is a significant diagnostic consideration and immunostaining for chromogranin and synaptophysin as well as some staining for cytokeratin would be … Intradural spinal tumours, although relatively uncommon, can be diagnostically challenging, and often result in significant morbidity. IMAGING FEATURES. Imaging tests. [Article in English, French] Crouzet G, Vasdev A, Lambrinidis M, Pasquier B, Pascal-Ortiz D, Mnif J, Chirossel JP, Le Bas JF. PATHOLOGY. In the cauda equina, myxopapillary ependymoma and paraganglioma are believed to arise from the filum terminale and have characteristic imaging manifestations based on their underlying pathologic features. After a 3-year disease-free follow-up, the patient was presented with symptoms of spinal cord compression due to spinal metastases in C2 and C3 vertebrae. (1)Department of Diagnostic Radiology, Keimyung University School of Medicine, Taegu, Korea. However, diagnosis of these rare tumors proves challenging due to the non-specific nature of radiological findings. Vol. Hence, it should be determined according to its biological behavior. Our patient represents what we believe to be the first reported case of a primary intradural thoracic paraganglioma. This article discusses the clinical characterics, normal anatamy, imaging findings and protocols, pathology, staging, and differential diagnosis for paragangliomas of the head and neck. They can be subdivided according to their cell of origin and whether they are within the cord (intramedullary) or intradural but extramedullary in location. Paragangliomas of the spine are uncommon lesions that usually present as intradural tumors within the cauda equina (19, 22). This article deals only with indications for adults. Paraganglioma of the lumbar spinal canal -- case report. No significant operative or postoperative complications occurred in any patient. Key points • Plain films are unlikely to demonstrate any abnormality, although vertebral scalloping or rarely calcification may be seen 4. The authors report three cases of spinal paragangliomas resulting in extradural spinal cord compression and their MR findings. He has special clinical interest in the use of dynamic imaging in the investigation of spinal instability disorders. The mechanisms are not defined for optic nervehead swelling in association with spinal tumors in general and paraganglioma in particular. The lesion can be easily mistaken for a lymph node. Paraganglioma of the Cauda Equina with Associated Intramedullary Cyst: MR Findings Scott H. Faro, Alan R. Turtz, Robert A. Koenigsberg, Feroze B. Mohamed, Cheng-Yu Chen, and Herman Stein Summary: The MR imaging features of a paraganglioma of the cauda equina with associated spinal … primary epidural paragangliomas in the thoracic spine (1-7].

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